Management of frailty at individual level – Frailty prevention
narrative literature review from the perspective of the European Joint Action on frailty – ADVANTAGE JA
DOI:
https://doi.org/10.14528/snr.2018.52.4.228Keywords:
elderly, prevention, nutrition, intervention, physical activityAbstract
Introduction: Frailty is a geriatric syndrome characterized by a diminished physiological reserve of multiple organs, which means increased of vulnerability of older people to adverse outcomes. As the process which leads to frailty can be decelerated or even completely reversed, early prevention interventions are crucial.
Methodology: A systematic literature search was conducted in the following databases: PubMed, Cochrane, Embase, Cinahl and UpToDate. The criterion in selecting the literature was that articles were published from 2002 to 2017. From 391.910 initial hits, 31 publications were selected.
Results: Early diagnosis of frailty and functional decline are considered effective measures against age-related comorbidities. Targeted interventions have a significant impact on preventing the progression of frailty and the negative consequences of frailty. Lifestyle, including physical activity (particularly resistance exercise) and nutrition (higher protein intake and vitamin D supplement), is a good measure for preventing disorders associated with age.
Conclusion: Targeted interventions have a significant modifiable influence on preventing frailty. Frailty management and early interventions comprise comprehensive and multidisciplinary approach including clinical management with physical management, nutrition and drugs.
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At, J., Dias, A., Philp, I., Beard, J., Patel, V. & Prince, M., 2015. Identifying common impairments in frail and dependent older people: validation of the COPE assessment for non-specialised health workers in low resource primary health care settings. BMC Geriatrics, 15, art. ID 123. https://doi.org/10.1186/s12877-015-0121-1 PMid:26467913; PMCid:PMC4607017
Bleijenberg, N., Drubbel, I., Ten Dam, V.H., Numans, M.E., Schuurmans, M.J. & de Wit, N.J., 2012. Proactive and integrated primary care for frail older people: design and methodological challenges of the Utrecht primary care PROactive frailty intervention trial (U-PROFIT). BMC Geriatrics, 12, art. ID 16. https://doi.org/10.1186/1471-2318-12-16 PMid:22533710; PMCid:PMC3373372
Bouillon, K., Kivimaki, M., Hamer, M., Sabia, S., Fransson, E.I., Singh-Manoux, A., et al., 2013. Measures of frailty in population based studies: an overview. BMC Geriatrics, 13, art. ID 64. https://doi.org/10.1186/1471-2318-13-64 PMid:23786540; PMCid:PMC3710231
British Geriatrics Society, 2014. Fit for Frailty: Consensus best practice guidance for the care of older people living with frailty in community and outpatient settings - a report from the British Geriatrics Society. London: The British Geriatrics Society. Available at: http://www.bgs.org.uk/campaigns/fff/fff_full.pdf [13. 2. 2018].
Buttery, A.K., Busch, M.A., Gaertner, B., Scheidt-Nave, C. & Fuchs, J., 2015. Prevalence and correlates of frailty among older adults: findings from the German health interview and examination survey. BMC Geriatrics, 15, art. ID 22. https://doi.org/10.1186/s12877-015-0022-3 PMid:25879568; PMCid:PMC4357063
Cadore, E.L., Rodríguez-Mañas, L., Sinclair, A. & Izquierdo, M., 2013. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: a systematic review. Rejuvenation Research, 16(2), pp. 105–114. https://doi.org/10.1089/rej.2012.1397 PMid:23327448; PMCid:PMC3634155
Campitelli, M.A., Bronskill, S.E., Hogan, D.B., Diong, C., Amuah, J.E., Gill, S., et al., 2016. The prevalence and health consequences of frailty in a population-based older home care cohort: a comparison of different measures. BMC Geriatrics, 16, art. ID 133. https://doi.org/10.1186/s12877-016-0309-z
Carretero, L., Navarro-Pardo, E. & Cano, A., 2015. Progression in healthy ageing: frailty, cognitive decline and gender in the
European Innovation Partnership for Active and Healthy Ageing. The European Journal of Psychiatry, article ID e1121. 29(4), pp. 231–237. https://doi.org/10.4321/S0213-61632015000400001
Clegg, A., Young, J., Iliffe, S., Rikkert, M. O. & Rockwood, K., 2013. Frailty in elderly people. Lancet, 381(9868), pp. 752–762. https://doi.org/10.1016/S0140-6736(12)62167-9
Coelho, T., Paúl, C., Gobbens, R.J.J. & Fernandes, L., 2015a. Determinants of frailty: the added value of assessing medication.Frontiers in Aging Neuroscience, 7, art. ID 56. https://doi.org/10.3389/fnagi.2015.00056 PMid:25954195; PMCid:PMC4404866
Coelho, T., Paúl, C., Gobbens, R.J.J. & Fernandes, L., 2015b. Frailty as a predictor of short-term adverse outcomes. PeerJ, 3, e1121. https://doi.org/10.7717/peerj.1121 PMid:26246968; PMCid:PMC4525687
Collard, R.M., Boter, H., Schoevers, R.A. & Oude Voshaar, R.C., 2012. Prevalence of frailty in community-dwelling older persons: a systematic review. Journal of the American Geriatrics Society, 60(8), pp. 1487–1492. https://doi.org/10.1111/j.1532-5415.2012.04054.x PMid:22881367
Drubbel, I., Numans, M. E., Kranenburg, G., Bleijenberg, N., de Wit, N. J. & Schuurmans, M. J., 2014. Screening for frailty in primary care: a systematic review of the psychometric properties of the frailty index in community-dwelling older people. BMC Geriatrics, 14, art. ID 27. https://doi.org/10.1186/1471-2318-14-27 PMid:24597624; PMCid:PMC3946826
Falsarella, G.R., Gasparotto, L.P.R., Barcelos, C.C., Coimbra, I.B., Moretto, M.C., Pascoa, M.A., et al., 2015. Body composition as a frailty marker for the elderly community. Clinical Interventions in Aging, 10, pp. 1661–1667. https://doi.org/10.2147/CIA.S84632 PMid:26527868; PMCid:PMC4621187
Fougère, B., Oustric, S., Delrieu, J., Chicoulaa, B., Escourrou, E., Rolland, et al., 2017. Implementing assessment of cognitive function and frailty into primary care: data from Frailty and Alzheimer disease prevention into Primary care (FAP) study pilot. Journal of the American Medical Directors Association, 18(1), pp. 47–52. https://doi.org/10.1016/j.jamda.2016.08.003 PMid:27650669
Gu, D., Yang, F. & Sautter, J., 2016. Socioeconomic status as a moderator between frailty and mortality at old ages. BMC Geriatrics, 16, art. ID 151. https://doi.org/10.1186/s12877-016-0322-2
Guessous, I., Luthi, J. C., Bowling, C. B., Theler, J.-M., Paccaud, F., Gaspoz, J.M., et al., 2014. Prevalence of frailty indicators and association with socioeconomic status in middle-aged and older adults in a Swiss region with universal health insurance coverage: a population-based cross-sectional study. Journal of Aging Research, 2014, art. ID e198603. https://doi.org/10.1155/2014/198603 PMid:25405033; PMCid:PMC4227447
Ilinca, S. & Calciolari, S., 2015. The patterns of health care utilization by elderly Europeans: frailty and its implications for health systems. Health Services Research, 50(1), pp. 305–320. https://doi.org/10.1111/1475-6773.12211 PMid:25139146; PMCid:PMC4319884
Kono, A., Izumi, K., Yoshiyuki, N., Kanaya, Y. & Rubenstein, L.Z., 2016. Effects of an updated preventive home visit program based on a systematic structured assessment of care needs for ambulatory frail older adults in Japan: a randomized controlled trial. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 71(12), pp. 1631–1637. https://doi.org/10.1093/gerona/glw068 PMid:27075895
Lee, D.R., Kawas, C.H., Gibbs, L. & Corrada, M.M., 2016. Prevalence of frailty and factors associated with frailty in individuals aged 90 and older: The 90+ Study. Journal of the American Geriatrics Society, 64(11), pp. 2257–2262. https://doi.org/10.1111/jgs.14317 PMid:27590837
Macklai, N.S., Spagnoli, J., Junod, J. & Santos-Eggimann, B., 2013. Prospective association of the SHARE-operationalized
frailty phenotype with adverse health outcomes: evidence from 60+ community-dwelling Europeans living in 11 countries. BMC Geriatrics, 13, art. ID 3. https://doi.org/10.1186/1471-2318-13-3 PMid:23286928; PMCid:PMC3585820
Malmstrom, T. K., Miller, D. K. & Morley, J. E., 2014. A comparison of four frailty models. Journal of the American Geriatrics Society, 62(4), pp. 721–726. https://doi.org/10.1111/jgs.12735. PMid:24635726; PMCid:PMC4519085
Mello, A. de C., Engstrom, E.M. & Alves, L.C., 2014. Healthrelated and socio-demographic factors associated with frailty in the elderly: a systematic literature review. Cadernos De Saude Publica, 30(6), pp. 1143–1168.
Metzelthin, S.F., Daniels, R., Van Rossum, E., De Witte, L., Van den Heuvel & W. J., Kempen, G. I., 2010. The psychometric properties of three self-report screening instruments for identifying frail older people in the community. BMC Public Health, 10, art. ID 176. https://doi.org/10.1186/1471-2458-10-176.
Mohandas, A., Reifsnyder, J., Jacobs, M. & Fox, T., 2011. Current and future directions in frailty research. Population Health Management, 14, art. ID 6. https://doi.org/10.1089/pop.2010.0066 PMid:22087470
Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G. & PRISMA Group., 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Medicine, 6(7), art. ID e1000097. https://doi.org/10.1371/journal.pmed.1000097 PMid:19621072; PMCid:PMC2707599
Morris, J.N., Howard, E.P. & Steel, K.R., 2016. Development of the interRAI home care frailty scale. BMC Geriatrics, 16, art. ID 188. https://doi.org/10.1186/s12877-016-0364-5
O'Caoimh, R., Gao, Y., Svendrovski, A., Healy, E., O'Connell, E., O'Keeffe, et al., 2014. Screening for markers of frailty and perceived risk of adverse outcomes using the Risk Instrument for Screening in the Community (RISC). BMC Geriatrics, 14, art. ID 104. https://doi.org/10.1186/1471-2318-14-104
Op het Veld, L.P.M., van Rossum, E., Kempen, G.I.J.M., de Vet, H.C.W., Hajema, K. & Beurskens, A.J.H.M., 2015. Fried phenotype of frailty: cross-sectional comparison of three frailty stages on various health domains. BMC Geriatrics, 15, art. ID 77. https://doi.org/10.1186/s12877-015-0078-0 PMid:26155837; PMCid:PMC4496916
Pahor, M., Guralnik, J. M., Ambrosius, W. T., Blair, S., Bonds, D. E. & Church, T. S., LIFE study investigators, 2014. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 311(23), pp. 2387–2396. https://doi.org/10.1001/jama.2014.5616 PMid:24866862; PMCid:PMC4266388
Polit, D.F., Beck & C.T., 2017. Nursing research: generating and assessing evidence for nursing practice. 10th ed. Philadelphia: Wolters Kluwer.
Serra-Prat, M., Papiol, M., Vico, J., Palomera, E., Sist, X. & Cabré, M., 2016. Factors associated with frailty in community dwelling elderly population: cross-sectional study. European Geriatric Medicine, 7(6), pp. 531–537. https://doi.org/10.1016/j.eurger.2016.09.005
Sheehan, K.J., O'Connell, M.D.L., Cunningham, C., Crosby, L. & Kenny, R.A., 2013. The relationship between increased body mass index and frailty on falls in community dwelling older adults. BMC Geriatrics, 13, art. ID 132. htps://doi.org/10.1186/1471-2318-13-132 PMid:24313947; PMCid:PMC4029500
Theou, O., Brothers, T.D., Mitnitski, A. & Rockwood, K., 2013. Operationalization of frailty using eight commonly used scales and comparison of their ability to predict all-cause mortality. Journal of the American Geriatrics Society, 61(9), pp. 1537–1551. https://doi.org/10.1111/jgs.12420. PMid:24028357
Uchmanowicz, I., Lisiak, M., Wontor, R. & Łoboz-Grudzień, K., 2015. Frailty in patients with acute coronary syndrome: comparison between tools for comprehensive geriatric assessment and the Tilburg Frailty Indicator. Clinical Interventions in Aging, 10, pp. 521–529. https://doi.org/10.2147/CIA.S78365 PMid:25767379; PMCid:PMC4354429
Van Kempen, J.A.L., Schers, H.J., Philp, I., Olde Rikkert, M.G.M. & Melis, R.J.F., 2015. Predictive validity of a two-step tool to map frailty in primary care. BMC Medicine, 13, art. ID 287. https://doi.org/10.1186/s12916-015-0519-9 PMid:26631066; PMCid:PMC4668681
Veninšek, G. & Gabrovec, B., 2018. Management of frailty at individual level - clinical management: systematic literature review. Zdravstveno Varstvo, 57(2), pp. 106–115. https://doi.org/ 10.2478/sjph-2018-0014.
Vermeulen, J., Neyens, J.C.L., van Rossum, E., Spreeuwenberg,M.D. & de Witte, L.P., 2011. Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: a systematic review. BMC Geriatrics, 11, art. ID 33. https://doi.org/10.1186/1471-2318-11-33 PMid:29651322; PMCid:PMC5894465
Vernerey, D., Anota, A., Vandel, P., Paget-Bailly, S., Dion, M., Bailly, et al., 2016. Development and validation of the FRAGIRE tool for assessment an older person's risk for frailty. BMC Geriatrics, 16, art. ID 187. https://doi.org/10.1186/s12877-016-0360-9
Villareal, D.T., Aguirre, L., Burke Gurney, A., Waters D.L., Sinacore D.R., Colombo, E., et al., 2017. Aerobic or resistance exercise, or both, in dieting obese older adults. New England Journal of Medicine, 376(20), pp. 1943–1955. https://doi.org/10.1056/NEJMoa1616338 PMid:28514618; PMCid:PMC5552187
World Health Organization, 2015. World report on ageing and health. Luxembourg. Available at: http://apps.who.int/iris/bitstream/10665/186463/1/9789240694811_eng.pdf?ua=1 [13. 2. 2018].
World Health Organization, 2017. Integrated Care for Older People (ICOPE): guidelines. Guidelines on community-level interventions to manage declines in intrinsic capacity. Switzerland. Available at: http://apps.who.int/iris/bitstream/10665/258981/1/9789241550109-eng.pdf?ua=1[10. 5. 2018].
Woo, J., Goggins, W., Sham, A. & Ho, S.C., 2005. Social determinants of frailty. Gerontology, 51(6), pp. 402–408. https://doi.org/10.1159/000088705 PMid:16299422
Woo, J., Zheng, Z., Leung, J. & Chan, P., 2015. Prevalence of frailty and contributory factors in three Chinese populations with different socioeconomic and healthcare characteristics. BMC Geriatrics, 15, art. ID 163. https://doi.org/10.1186/s12877-015-0160-7 PMid:26652647; PMCid:PMC4675032
Young, A.C.M., Glaser, K., Spector, T.D. & Steves, C.J., 2016. The identification of hereditary and environmental determinants of frailty in a cohort of UK twins: twin research and human Genetics. The Official Journal of the nternational Society for Twin Studies, 19(6), pp. 600–609. https://doi.org/10.1017/thg.2016.72 PMid:27719687
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