Farmakološka in nefarmakološka terapija za zdravljenje primarne dismenoreje:

sistematični pregled literature

  • Aleksandra Kavšak Ortopedska bolnišnica Valdoltra, Jadranska cesta 31, 6280 Ankaran, Slovenija
  • Liridon Avdylaj Splošna bolnišnica Izola, Polje 40, 6310 Izola, Slovenija
Ključne besede: zmanjšanje bolečine, boleča menstruacija, kombinirana terapija

Povzetek

Uvod: V prispevku smo na podlagi sistematičnega pregleda literature identificirali različne oblike farmakološkega in nefarmakološkega zdravljenja, ki lahko ženskam s primarno dismenorejo pomagajo zmanjšati intenziteto bolečine. Namen raziskave je bil namreč ugotoviti oblike farmakološke in nefarmakološke terapije za zmanjšanje bolečine pri primarni dismenoreji.
Metode: Za iskanje literature so bile uporabljene podatkovne baze: CINAHL, Medline, ScienceDirect in Cochrane Library.  Uporabljeni so bili naslednji iskalni pojmi: primarna dismenoreja, menstrualna bolečina, farmakološko zdravljenje, nefarmakološko zdravljenje; v angleškem jeziku: primary dysmenorrhea, menstrual pain, pharmalogical intervention,  non-pharmacological intervention. Iskanje je bilo omejeno na znanstvene revije, recenzirane publikacije, dostopne v  celotnem besedilu, besedila, objavljena v angleškem jeziku v obdobju 2007–2017. Skupaj je bilo  identificiranih 571 zadetkov, v končno analizo je bilo vključenih 13 raziskav, ki so ustrezale namenu raziskave.
Rezultati: Analiziranih je bilo 13 raziskav, od tega pet farmakoloških in osem nefarmakoloških oblik zdravljenja. Rezultati raziskave so pokazali, da nesteroidna protivnetna zdravila ponujajo precejšnje zmanjšanje bolečine pri večini žensk s  primarno dismenorejo. Ugotovitve kažejo, da vse oblike nefarmakološkega zdravljenja niso priporočljive in pri pacientkah s primarno dismenorejo ne pomagajo zmanjšati intenzitete bolečine. 
Diskusija in zaključek: Rezultati sistematičnega pregleda literature kažejo, da farmakološko zdravljenje učinkoviteje zmanjšuje intenziteto bolečine, saj se učinek delovanja zdravila izkaže v eni uri po zaužitju, vendar povzroča nekatere stranske učinke.

Prenosi

Podatki o prenosih še niso na voljo.

Biografije avtorja

Aleksandra Kavšak, Ortopedska bolnišnica Valdoltra, Jadranska cesta 31, 6280 Ankaran, Slovenija

dipl. m. s.

Liridon Avdylaj, Splošna bolnišnica Izola, Polje 40, 6310 Izola, Slovenija

dipl. zn.

Literatura

Abaraogu, U.O., Igwe, S.E. & Tabansi-Ochiogu, C.S., 2016. Effectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: a systematic review with meta- and sensitivity analysis. Complementary Therapies in Clinical Practice, 25(1), pp. 92–105. https://doi.org/10.1016/j.ctcp.2016.09.003 PMid:27863617

Abaraogu, U.O. & Tabanasi-Ochuogu, C.S., 2015. As acupressure decreases pain, acupuncture may improve some aspects of quality of life for women with primary dysmenorrhea: a systematic review with meta-analysis. Journal of Acupuncture and Meridian Studies, 8(5), pp. 220–228. https://doi.org/10.1016/j.jams.2015.06.010 PMid:26433798

Aktaş, D., 2015. Prevalence and factors affecting dysmenorrhea in female university students: effect on general comfort level. Pain Management Nursing, 16(4), pp. 534–543. https://doi.org/10.1016/j.pmn.2014.10.004 PMid:26256218

Al-Jefout, M. & Nawaiseh, N., 2016. Continuous Norethisterone Acetate versus Cyclical Drospirenone 3 mg / Ethinyl Estradiol 20 μg for the management of primary dysmenorrhea in young adult women. Journal of Pediatric and Adolescent Gynecology, 29(2), pp. 143–147. https://doi.org/10.1016/j.jpag.2015.08.009 PMid:26342733

Antao, V., Black, A., Burnett, M., Feldman, K., Lea, R. & Robert M., 2005. Primary dysmenorrhea consensus guideline. SOGC Clinical Practice Guideline, 169, pp. 1117–1130.

CAPS, Critical appraisal skills programme, 2014. CASP Checklist. Available at: http://www.casp-uk.net/casp-tools-checklists [10. 4. 2017].

Tu, C.H., Niddam, H.D., Chao, H.T., Liu, R.S., Hwang, R.J., et al., 2009. Abnormal cerebral metabolism during menstrual pain in primary dysmenorrhea. NeuroImage, 47(1), pp. 28–35. https://doi.org/10.1016/j.neuroimage.2009.03.080 PMid:19362153

Daniels, S., Robbins, J., West, C.R., Nemeth, M.A., et al., 2009. Celecoxib in the treatment of primary dysmenorrhea: results from two randomized, double-blind, active and placebocontrolled, crossover Studies. Clinical Therapeutic, 31(6), pp. 1192–1208. https://doi.org/10.1016/j.clinthera.2009.06.003 PMid:19695387

Davari, M., Khoshrang, N. & Reihani, M., 2014. The aromatherapy effect of rosemary and lavander on primary dysmenorrhea: a clinical controlled trial. Journal of Isfahan Medical School, 32(290), pp. 929–937.

Ghodsi, Z. & Astoghiri, M., 2014. The effect of Fennel on pain quality, symptoms, and menstrual duration in primary dysmenorrhea. Journal of Pediatric and Adolescent Gynecology, 27(5), pp. 283–286. https://doi.org/10.1016/j.jpag.2013.12.003 PMid:25085020

Grimshaw, J., Eccles, M., Thomas, R., MacLennan, G., Ramsay, C., Fraser, C., et al., 2006. Toward evidence-based quality improvement: evidence (and its limitations) of the effectiveness of guideline dissemination and implementation strategies 1966–1998. Journal of General Internal Medicine, 21, pp. s14–s20. http://dx.doi.org/10.1007/s11606-006-0269-7 PMid:16637955; PMCid:PMC2557130

Igwea, S.E., Tabansi-Ochuogu, C.S. & Abaraogu, U.O., 2016. TENS and heat therapy for pain relief and quality of life improvement in individuals with primary dysmenorrhea: a systematic review. Complementary Therapies in Clinical Practice, 24(5), pp. 86–91. https://doi.org/10.1016/j.ctcp.2016.05.001 PMid:27502806

Kannan, P. & Claydon, L.S., 2014. Some physiotherapy treatments may relieve menstrual pain in women with primary dysmenorrhea: a systematic review. Journal of Physiotherapy, 60(1), pp. 13–21. https://doi.org/10.1016/j.jphys.2013.12.003 PMid:24856936

Kannan, P., Chapple, C.M., Miller, D., Claydon, L.S. & Blaxter, D.G., 2015. Menstrual pain and quality of life in women with primary dysmenorrhea: rationale, design, and interventions of a randomized controlled trial of effects of a treadmill-based

exercise intervention. Contemporary Clinical Trials, 42(1), pp. 81–89. https://doi.org/10.1016/j.cct.2015.03.010 PMid:25839713

Kashefi, F., Khajehei, M., Tabatabaeichehr., M., Alavinia, M. & Asili, J., 2014. Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial. Pain Management Nursing, 15(4), pp. 826–833. https://doi.org/10.1016/j.pmn.2013.09.001 PMid:24559600

Lee, H., Choi, T.Y., Myung, C.S., Lee, J.A. & Lee, M.S., 2016. Herbal medicine (Shaofu Zhuyu decoction) for treating primary dysmenorrhea: a systematic review of randomized clinical trials. Maturitas, 86(1), pp. 64–73. https://doi.org/10.1016/j.maturitas.2016.01.012 PMid:26921931

Li, L., Huangfu, L., Chai, H., He, W., Song, H., Zou, X., et al., 2012. Development of a functional and emotional measure of dysmenorrhea (FEMD) in Chinese university women. Health Care for Women International, 33(1), pp. 97–108. https://doi.org/10.1080/07399332.2011.603863 PMid:22242651

Ogunnaike, P.O., Olatunji, S.J., Owolabi, J.O., Lawrence, I.G. & Olanrewaju, J.A., 2016. A case study of the prevalence of dysmenorrhea and its effects among females of different age groups. Journal of Experimental and Integrative Medicine, 6(3), pp. 125–133. https://doi.org/10.5455/jeim.180916.or.161

Ortiz, M.I., Cortés-Márquez, S.K., Romero-Quezada, L.C., Murguia-Canovas, G., & Jaramillo-Diaz, A.P., 2015. Effect of a physiotherapy program in women with primary dysmenorrhea. European Journal of Obstetrics and Gynecology and Reproductive Biology, 194(1), pp. 24–29. https://doi.org/10.1016/j.ejogrb.2015.08.008 PMid:26319652

Ozgoli, G., Goli, M. & Moattar, F., 2009. Comparison of effects of ginger, mefenamic acid, and Ibuprofen on pain in women with primary dysmenorrhea. The Journal of alternative and complementary medicine, 15(2), pp. 129–132. https://doi.org/10.1089/acm.2008.0311 PMid:19216660

Moher, D., Liberati, A., Tetzlaff, J. & Altman, D.G., 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Journal of Clinical Epidemiology, 62(10), pp. 1006–1012. http://dx.doi.org/10.1016/j.jclinepi.2009.06.005 PMid:19631508

Patel, J.C., Patel., P.B., Acharya, H., Nakum, K. & Tripathi, C.B., 2015. Efficacy and safety of lornoxicam vs ibuprofen in primary dysmenorrhea: a randomized, double-blind, double dummy, active-controlled, cross over study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 188(1), pp. 118–123. https://doi.org/10.1016/j.ejogrb.2015.03.005 PMid:25808572

Potur, D.C., Bilgin, N.C. & Komurcu, N., 2014. Prevalence of dysmenorrhea in university students in Turkey: effect on daily activaties and evaluation of different pain management methods. Pain Management Nursing, 15(4), pp. 768–777. https://doi.org/10.1016/j.pmn.2013.07.012 PMid:24230963

Sut, N. & Kahyaoglu-Sut, H., 2017. Effect of aromatherapy massage on pain in primary dysmenorrhea: a meta-analysis. Complementary Therapies in Clinical Practice, 27(1), pp. 5–10. https://doi.org/10.1016/j.ctcp.2017.01.001 PMid:28438280

Topalović, Z., 2010. Značajke i nepravilnosti menstruacijskog ciklusa. Medicus, 19(1), pp. 19–25. Available at: https://hrcak.srce.hr/60001 [10. 4. 2017].

Unsal, A., Ayranci, U., Tozun, M., Arslan, G. & Calik, E., 2010. Prevalence of dysmenorrhea and its effect on quality of life among a group of female university students. Upsala Journal of Medical Sciences, 115(1), pp. 138–145. https://doi.org/10.3109/03009730903457218 PMid:20074018; PMCid:PMC2853792

Uysal, M., Doğru, H.Y., Sapmaz, E., Tas, U., Çakmak, B., Ozsoy, A.Z., et al., 2016. Investigating the effect of rose essential oil in patients with primary dysmenorrhea. Complementary Therapies in Clinical Practice, 24(1), pp. 45–49. https://doi.org/10.1016/j.ctcp.2016.05.002 PMid:27502800

Zahradnik, H.P., Hanjalic-Beck, A. & Groth, K., 2010. Nonsteroidal anti-inflammatory drugs and hormonal contraceptives for pain relief from dysmenorrhea: a review. Contraception, 81(2), pp. 185–196. https://doi.org/10.1016/j.contraception.2009.09.014 PMid:20159173

Zhu, X., Bensoussan, A., Zhu, L., Qian, J., Xu, M., Zhou, C., et al., 2009. Primary dysmenorrhoea: a comparative study on Australian and Chinese women. Complementary Therapies in Medicine, 17(2), pp. 155–160. https://doi.org/10.1016/j.ctim.2008.10.001 PMid:19398069

Objavljeno
2018-03-14
Kako citirati
Kavšak, A. in Avdylaj, L. (2018) Farmakološka in nefarmakološka terapija za zdravljenje primarne dismenoreje:, Obzornik zdravstvene nege, 52(2), str. 118-127. doi: 10.14528/snr.2018.52.2.191.
Rubrike
Pregledni znanstveni članek