Pharmacological and non-pharmacological therapy for the treatment of primary dysmenorrhea
a systematic review of literature
DOI:
https://doi.org/10.14528/snr.2018.52.2.191Keywords:
painful menstruation, pain reduction, combined therapyAbstract
Introduction: The article is based on a systematic review of the literature and identifies the different forms of pharmacological and non-pharmacological treatments which can help women with primary dysmenorrhea to reduce pain intensities. The aim of the study was to determine the forms of pharmacological and nonpharmacological therapy for the reduction of pain in primary dysmenorrhea through literature review.
Methods: The databases that were searched included CINAHL, Medline, ScienceDirect and Cochrane Library. The following search terms were used: primary dysmenorrhea, menstrual pain, pharmacological intervention and non-pharmacological intervention. The search was limited to full text available in English language, published between 2007 and 2017 peer reviewed publications. The search yielded 571 results, but the final review included 13 studies.
Results: 13 studies were reviewed, 5 of which were about pharmacological treatments and 8 of nonpharmacological treatments. The results of the systematic review showed that non-steroidal anti-inflammatory drugs offer a significant reduction of pain in most women with primary dysmenorrhea. Findings suggest that all forms of non-pharmacological treatment are not recommended and do not help to reduce pain intensity in patients with primary dysmenorrhea.
Discussion and conclusion: The results of a systematic review of literature have shown that pharmacological treatment is more effective in reducing pain intensity as the drug takes effect within one hour after taking it, but causes some side effects.
Downloads
Metrics
References
Abaraogu, U.O., Igwe, S.E. & Tabansi-Ochiogu, C.S., 2016. Effectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: a systematic review with meta- and sensitivity analysis. Complementary Therapies in Clinical Practice, 25(1), pp. 92–105. https://doi.org/10.1016/j.ctcp.2016.09.003 PMid:27863617
Abaraogu, U.O. & Tabanasi-Ochuogu, C.S., 2015. As acupressure decreases pain, acupuncture may improve some aspects of quality of life for women with primary dysmenorrhea: a systematic review with meta-analysis. Journal of Acupuncture and Meridian Studies, 8(5), pp. 220–228. https://doi.org/10.1016/j.jams.2015.06.010 PMid:26433798
Aktaş, D., 2015. Prevalence and factors affecting dysmenorrhea in female university students: effect on general comfort level. Pain Management Nursing, 16(4), pp. 534–543. https://doi.org/10.1016/j.pmn.2014.10.004 PMid:26256218
Al-Jefout, M. & Nawaiseh, N., 2016. Continuous Norethisterone Acetate versus Cyclical Drospirenone 3 mg / Ethinyl Estradiol 20 μg for the management of primary dysmenorrhea in young adult women. Journal of Pediatric and Adolescent Gynecology, 29(2), pp. 143–147. https://doi.org/10.1016/j.jpag.2015.08.009 PMid:26342733
Antao, V., Black, A., Burnett, M., Feldman, K., Lea, R. & Robert M., 2005. Primary dysmenorrhea consensus guideline. SOGC Clinical Practice Guideline, 169, pp. 1117–1130.
CAPS, Critical appraisal skills programme, 2014. CASP Checklist. Available at: http://www.casp-uk.net/casp-tools-checklists [10. 4. 2017].
Tu, C.H., Niddam, H.D., Chao, H.T., Liu, R.S., Hwang, R.J., et al., 2009. Abnormal cerebral metabolism during menstrual pain in primary dysmenorrhea. NeuroImage, 47(1), pp. 28–35. https://doi.org/10.1016/j.neuroimage.2009.03.080 PMid:19362153
Daniels, S., Robbins, J., West, C.R., Nemeth, M.A., et al., 2009. Celecoxib in the treatment of primary dysmenorrhea: results from two randomized, double-blind, active and placebocontrolled, crossover Studies. Clinical Therapeutic, 31(6), pp. 1192–1208. https://doi.org/10.1016/j.clinthera.2009.06.003 PMid:19695387
Davari, M., Khoshrang, N. & Reihani, M., 2014. The aromatherapy effect of rosemary and lavander on primary dysmenorrhea: a clinical controlled trial. Journal of Isfahan Medical School, 32(290), pp. 929–937.
Ghodsi, Z. & Astoghiri, M., 2014. The effect of Fennel on pain quality, symptoms, and menstrual duration in primary dysmenorrhea. Journal of Pediatric and Adolescent Gynecology, 27(5), pp. 283–286. https://doi.org/10.1016/j.jpag.2013.12.003 PMid:25085020
Grimshaw, J., Eccles, M., Thomas, R., MacLennan, G., Ramsay, C., Fraser, C., et al., 2006. Toward evidence-based quality improvement: evidence (and its limitations) of the effectiveness of guideline dissemination and implementation strategies 1966–1998. Journal of General Internal Medicine, 21, pp. s14–s20. http://dx.doi.org/10.1007/s11606-006-0269-7 PMid:16637955; PMCid:PMC2557130
Igwea, S.E., Tabansi-Ochuogu, C.S. & Abaraogu, U.O., 2016. TENS and heat therapy for pain relief and quality of life improvement in individuals with primary dysmenorrhea: a systematic review. Complementary Therapies in Clinical Practice, 24(5), pp. 86–91. https://doi.org/10.1016/j.ctcp.2016.05.001 PMid:27502806
Kannan, P. & Claydon, L.S., 2014. Some physiotherapy treatments may relieve menstrual pain in women with primary dysmenorrhea: a systematic review. Journal of Physiotherapy, 60(1), pp. 13–21. https://doi.org/10.1016/j.jphys.2013.12.003 PMid:24856936
Kannan, P., Chapple, C.M., Miller, D., Claydon, L.S. & Blaxter, D.G., 2015. Menstrual pain and quality of life in women with primary dysmenorrhea: rationale, design, and interventions of a randomized controlled trial of effects of a treadmill-based
exercise intervention. Contemporary Clinical Trials, 42(1), pp. 81–89. https://doi.org/10.1016/j.cct.2015.03.010 PMid:25839713
Kashefi, F., Khajehei, M., Tabatabaeichehr., M., Alavinia, M. & Asili, J., 2014. Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial. Pain Management Nursing, 15(4), pp. 826–833. https://doi.org/10.1016/j.pmn.2013.09.001 PMid:24559600
Lee, H., Choi, T.Y., Myung, C.S., Lee, J.A. & Lee, M.S., 2016. Herbal medicine (Shaofu Zhuyu decoction) for treating primary dysmenorrhea: a systematic review of randomized clinical trials. Maturitas, 86(1), pp. 64–73. https://doi.org/10.1016/j.maturitas.2016.01.012 PMid:26921931
Li, L., Huangfu, L., Chai, H., He, W., Song, H., Zou, X., et al., 2012. Development of a functional and emotional measure of dysmenorrhea (FEMD) in Chinese university women. Health Care for Women International, 33(1), pp. 97–108. https://doi.org/10.1080/07399332.2011.603863 PMid:22242651
Ogunnaike, P.O., Olatunji, S.J., Owolabi, J.O., Lawrence, I.G. & Olanrewaju, J.A., 2016. A case study of the prevalence of dysmenorrhea and its effects among females of different age groups. Journal of Experimental and Integrative Medicine, 6(3), pp. 125–133. https://doi.org/10.5455/jeim.180916.or.161
Ortiz, M.I., Cortés-Márquez, S.K., Romero-Quezada, L.C., Murguia-Canovas, G., & Jaramillo-Diaz, A.P., 2015. Effect of a physiotherapy program in women with primary dysmenorrhea. European Journal of Obstetrics and Gynecology and Reproductive Biology, 194(1), pp. 24–29. https://doi.org/10.1016/j.ejogrb.2015.08.008 PMid:26319652
Ozgoli, G., Goli, M. & Moattar, F., 2009. Comparison of effects of ginger, mefenamic acid, and Ibuprofen on pain in women with primary dysmenorrhea. The Journal of alternative and complementary medicine, 15(2), pp. 129–132. https://doi.org/10.1089/acm.2008.0311 PMid:19216660
Moher, D., Liberati, A., Tetzlaff, J. & Altman, D.G., 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Journal of Clinical Epidemiology, 62(10), pp. 1006–1012. http://dx.doi.org/10.1016/j.jclinepi.2009.06.005 PMid:19631508
Patel, J.C., Patel., P.B., Acharya, H., Nakum, K. & Tripathi, C.B., 2015. Efficacy and safety of lornoxicam vs ibuprofen in primary dysmenorrhea: a randomized, double-blind, double dummy, active-controlled, cross over study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 188(1), pp. 118–123. https://doi.org/10.1016/j.ejogrb.2015.03.005 PMid:25808572
Potur, D.C., Bilgin, N.C. & Komurcu, N., 2014. Prevalence of dysmenorrhea in university students in Turkey: effect on daily activaties and evaluation of different pain management methods. Pain Management Nursing, 15(4), pp. 768–777. https://doi.org/10.1016/j.pmn.2013.07.012 PMid:24230963
Sut, N. & Kahyaoglu-Sut, H., 2017. Effect of aromatherapy massage on pain in primary dysmenorrhea: a meta-analysis. Complementary Therapies in Clinical Practice, 27(1), pp. 5–10. https://doi.org/10.1016/j.ctcp.2017.01.001 PMid:28438280
Topalović, Z., 2010. Značajke i nepravilnosti menstruacijskog ciklusa. Medicus, 19(1), pp. 19–25. Available at: https://hrcak.srce.hr/60001 [10. 4. 2017].
Unsal, A., Ayranci, U., Tozun, M., Arslan, G. & Calik, E., 2010. Prevalence of dysmenorrhea and its effect on quality of life among a group of female university students. Upsala Journal of Medical Sciences, 115(1), pp. 138–145. https://doi.org/10.3109/03009730903457218 PMid:20074018; PMCid:PMC2853792
Uysal, M., Doğru, H.Y., Sapmaz, E., Tas, U., Çakmak, B., Ozsoy, A.Z., et al., 2016. Investigating the effect of rose essential oil in patients with primary dysmenorrhea. Complementary Therapies in Clinical Practice, 24(1), pp. 45–49. https://doi.org/10.1016/j.ctcp.2016.05.002 PMid:27502800
Zahradnik, H.P., Hanjalic-Beck, A. & Groth, K., 2010. Nonsteroidal anti-inflammatory drugs and hormonal contraceptives for pain relief from dysmenorrhea: a review. Contraception, 81(2), pp. 185–196. https://doi.org/10.1016/j.contraception.2009.09.014 PMid:20159173
Zhu, X., Bensoussan, A., Zhu, L., Qian, J., Xu, M., Zhou, C., et al., 2009. Primary dysmenorrhoea: a comparative study on Australian and Chinese women. Complementary Therapies in Medicine, 17(2), pp. 155–160. https://doi.org/10.1016/j.ctim.2008.10.001 PMid:19398069
Downloads
Published
How to Cite
Issue
Section
License
As the author undersigned hereby, I transfer, assign, or otherwise convey the following authorship rights as comprised in the Copyright and Related Rights Act (CRRA) to the Slovenian Nursing Review, Ob železnici 30A, 1000 Ljubljana: the right of reproduction - the exclusive right to fix the work in a material medium or in another copy directly or indirectly, temporarily or permanently, by any means and in any digital form, in whole or in part (CRRA, Article 23); the right of distribution (CRRA, Article 24); the right of making a work available and accessible through the internet (CRRA, Article 32a); the right of transformation, especially the exclusive right to translate a pre-existing work (CRRA, Article 33). The transfer of author rights applies to the article in its entirety, including pictorial and/or graphic works and possible supplements. The transfer of rights is exclusive and unlimited in duration or territory.