Intervencije medicinskih sester za izboljšanje adherence pri starejših odraslih v domačem okolju

integrativni pregled literature

Avtorji

DOI:

https://doi.org/10.14528/snr.2025.59.3.3305

Ključne besede:

adherenca za zdravila, starejši odrasli, domače okolje, zdravstvena nega, intervencije

Povzetek

Uvod: Starajoče se prebivalstvo in porast kroničnih obolenj povečujeta uporabo zdravil, vendar je adherenca pri zdravljenju z zdravili pri starejših odraslih, ki živijo doma, slabo raziskana. Namen raziskave je predstaviti dejavnike adherence in preučiti vlogo medicinskih sester pri preprečevanju ter zmanjševanju neadherence v domačem okolju.
Metode: Pregledali smo literaturo v zbirkah Medline, CINAHL, Cochrane Library, PubMed, ScienceDirect, Web of Science, Wiley in ProQuest z uporabo iskalnih pojmov: aged, home health care, medication adherence, nurse. Pregledali smo recenzirane objave od leta 2000 do 2025. V analizo smo vključili enaindvajset raziskav, ocenili njihovo kakovost (s standardi STROBE in COREQ) in izvedli tematsko analizo vsebine.
Rezultati: Po analizi smo poudarili več področij, ki jih medicinske sestre obravnavajo pri obravnavi neadherence: izobraževanje pacientov, motivacija, spodbujanje k uporabi pripomočkov, vključevanje in sodelovanje z drugimi strokovnjaki.
Diskusija in zaključek: Medicinske sestre imajo osrednjo vlogo pri identifikaciji in obravnavi neadherence v zdravljenju z zdravili pri starejših odraslih, ki živijo v domačem okolju. Njihove intervencije morajo biti prilagojene posameznikovim potrebam, zahtevam terapije in graditi na strokovnih kompetencah. Zaradi razpršenih rezultatov in omejenih dokazov o učinkovitosti intervencij so potrebne nadaljnje raziskave za razvoj optimalnih, na dokazih temelječih načinov v zdravstveni negi.

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Literatura

Aljofan, M., Oshibayeva, A., Moldaliyev, I., Saruarov, Y., Maulenkul, T., & Gaipov, A. (2023). The rate of medication nonadherence and influencing factors: A systematic review. Electronic Journal of General Medicine, 20(3), Article em471. https://doi.org/10.29333/ejgm/12946

Bailey, S. C., Opsasnick, L. A., Curtis, L. M., Federman, A. D., Benavente, J. Y., O'Conor, R., & Wolf, M. S. (2020). Longitudinal investigation of older adults' ability to self-manage complex drug regimens. Journal of the American Geriatrics Society, 68(3), 569–575. https://doi.org/10.1111/jgs.16255 PMid:31765007; PMCid:PMC7056504

Baryakova, T. H., Pogostin, B. H., Langer, R., & McHugh, K. J. (2023). Overcoming barriers to patient adherence: The case for developing innovative drug delivery systems. Nature Reviews Drug Discovery, 22(5), 387–409. https://doi.org/10.1038/s41573-023-00670-0 PMid:36973491; PMCid:PMC10041531

Berardinelli, D., Conti, A., Hasnaoui, A., Casabona, E., Martin, B., Campagna, S., & Dimonte, V. (2024). Nurse-led interventions for improving medication adherence in chronic diseases: A systematic review. Healthcare (Basel), 12(23), Article 2337. https://doi.org/10.3390/healthcare12232337 PMid:39684959; PMCid:PMC11641167

Bizjak Končar, A., Divjak Race, D., Gabrovšek, D., Gliha Komac, N., Jakop, N., Ježovnik, J., Kocijančič, G., Kramberger, J., Križman, M., Lah, M., Marolt, P., Novak, T., Oblak, R., Petek, U., Rozman, E., Smole, M., Tomšič, L., Vidmar, B., Zupančič, K., & Žele, A. (2023). SSKJ, Slovar slovenskega knjižnega jezika. Založba ZRC.

Cheng, C., Yu, H., & Wang, Q. (2023). Nurses' experiences concerning older adults with polypharmacy: A meta-synthesis of qualitative findings. Healthcare (Basel), 11(3), Article 334. https://doi.org/10.3390/healthcare11030334 PMid:36766909; PMCid:PMC9914425

Conn, V. S., Ruppar, T. M., Enriquez, M., & Cooper, P. (2016). Medication adherence interventions that target subjects with adherence problems: Systematic review and meta-analysis. Research in Social and Administrative Pharmacy, 12(2), 218–246. https://doi.org/10.1016/j.sapharm.2015.06.001 PMid:26164400; PMCid:PMC4679728

Conn, V. S., Ruppar, T. M., Enriquez, M., Cooper, P. S., & Chan, K. C. (2015). Healthcare provider targeted interventions to improve medication adherence: Systematic review and meta-analysis. International Journal of Clinical Practice, 69(8), 889–899. https://doi.org/10.1111/ijcp PMid:25728214; PMCid:PMC5673083

Cross, A. J., Elliott, R. A., Petrie, K., Kuruvilla, L., & George, J. (2020). Interventions for improving medication-taking ability and adherence in older adults prescribed multiple medications. Cochrane Database of Systematic Review, 5(5), Article CD012419. https://doi.org/10.1002/14651858.CD012419.pub2 PMid:32383493; PMCid:PMC7207012

DeKoekkoek, T., Given, B., Given, C. W., Ridenour, K., Schueller, M., & Spoelstra, S. L. (2015). mHealth SMS text messaging interventions and to promote medication adherence: An integrative review. Journal of Clinical Nursing, 24(19/20), 2722–2735. https://doi.org/10.1111/jocn.12918 PMid:26216256

Delavar, F., Pashaeypoor, S., & Negarandeh, R. (2020). The effects of self-management education tailored to health literacy on medication adherence and blood pressure control among elderly people with primary hypertension: A randomized controlled trial. Patient Education and Counseling, 103(2), 336–342. https://doi.org/10.1016/j.pec.2019.08.028 PMid:31451361

Dumitrescu, I., Casteels, M., De Vliegher, K., Hubens, C., & Dilles, T. (2025). Home care patient's experiences and medication burden related to high-risk medication use: A cross-sectional study. International Journal of Older People Nursing, 20(1), Article e70003. https://doi.org/10.1111/opn.70003 PMid:39663656

Ge, L., Heng, B. H., & Yap, C. W. (2023). Understanding reasons and determinants of medication non-adherence in community-dwelling adults: A cross-sectional study comparing young and older age groups. BMC Health Services Research, 23(1), Article 905. https://doi.org/10.1186/s12913-023-09904-8 PMid:37620970; PMCid:PMC10464472

Griffiths, R., Johnson, M., Piper, M., & Langdon, R. (2004). A nursing intervention for the quality use of medicines by elderly community clients. International Journal of Nursing Practice, 10(4), 166–176. https://doi.org/10.1111/j.1440-172X.2004.00476.x PMid:15265227

Gudala, M., Ross, M. E. T., Mogalla, S., Lyons, M., Ramaswamy, P., & Roberts, K. (2022). Benefits of, barriers to, and needs for an artificial intelligence-powered medication information voice chatbot for older adults: Interview study with geriatrics experts. JMIR Aging, 5(2), Article e32169. https://doi.org/10.2196/32169 PMid:35482367; PMCid:PMC9100542

Han, Y., Chen, J., Xu, Y., Huang, P., & Hou, L. (2024). Nurse-led medication management as a critical component of transitional care for preventing drug-related problems. Aging Clinical and Experimental Research, 36(1), Article 151. https://doi.org/10.1007/s40520-024-02799-3 PMid:39060872; PMCid:PMC11282160

Henriques, M. A., Costa, M. A., & Cabrita, J. (2012). Adherence and medication management by the elderly. Journal of Clinical Nursing, 21(21/22), 3096–3105. https://doi.org/10.1111/j.1365-2702.2012.04144.x PMid:22882751

Jafari, F., Khatony, A., & Rahmani, E. (2015). Prevalence of self-medication among the elderly in Kermanshah-Iran. Global Journal of Health Science, 7(2), 360–365. https://doi.org/10.5539/gjhs.v7n2p360

Janežič, A., & Kos, M. (2015). Z dokazi podprte intervencije za izboljšanje sodelovanja pri zdravljenju z zdravili. Farmacevtski vestnik, 66(5), 378–386.

Jin, H., Kim, Y., & Rhie, S. J. (2016). Factors affecting medication adherence in elderly people. Patient Preference and Adherence, 10, 2117–2125. https://doi.org/10.2147/ppa.s118121 PMid:27799748; PMCid:PMC5077271

Kaasalainen, S., Dolovich, L., Papaioannou, A., Holbrook, A., Lau, E., Ploeg, J., Levine, M., Cosby, J., & Emily, A. (2011). The process of medication management for older adults with dementia. Journal of Nursing and Healthcare of Chronic Illness, 3(4), 407–418. https://doi.org/10.1111/j.1752-9824.2011.01114.x

Kajander-Unkuri, S., Vaismoradi, M., Katajisto, J., Kangasniemi, M., & Turjamaa, R. (2023). Effect of robot for medication management on home care professionals’ use of working time in older people's home care: A non-randomized controlled clinical trial. BMC Health Services Research, 23(1), Article 1344. https://doi.org/10.1186/s12913-023-10367-0 PMid:38042773; PMCid:PMC10693699

Kengne, A. P., Brière, J. B., Zhu, L., Li, J., Bhatia, M. K., Atanasov, P., & Khan, Z. M. (2024). Impact of poor medication adherence on clinical outcomes and health resource utilization in patients with hypertension and/or dyslipidemia: Systematic review. Expert Review of Pharmacoeconomics & Outcomes Research, 24(1), 143–154. https://doi.org/10.1080/14737167.2023.2266135 PMid:37862440

Lagerin, A., Carlsson, A. C., Nilsson, G., Westman, J., & Törnkvist, L. (2014). District nurses' preventive home visits to 75-year-olds: An opportunity to identify factors related to unsafe medication management. Scandinavian Journal of Public Health, 42(8), 786–794. https://doi.org/10.1177/1403494814550680 PMid:25260640

Lauffenburger, J. C., Khan, N. F., Brill, G., & Choudhry, N. K. (2019). Quantifying social reinforcement among family members on adherence to medications for chronic conditions: A US-based retrospective cohort study. Journal of General Internal Medicine, 34(6), 855–861. https://doi.org/10.1007/s11606-018-4654-9 PMid:30406566; PMCid:PMC6544705

Liquori, G., Panattoni, N., De Leo, A., Dionisi, S., Giannetta, N., Gasperi, B., Orsi, G. B., Di Muzio, F., Di Muzio, M., & Di Simone, E. (2024). A phenomenological approach to medication adherence in elderly patients: A qualitative study. Healthcare, 12(19), Article 1925. https://doi.org/10.3390/healthcare12191925 PMid:39408105; PMCid:PMC11476112

Liu, J., Yu, Y., Yan, S., Zeng, Y., Su, S., He, T., Wang, Z., Ding, Q., Zhang, R., Li, W., Wang, X., Zhang, L., & Yue, X. (2023). Risk factors for self-reported medication adherence in community-dwelling older patients with multimorbidity and polypharmacy: A multicenter cross-sectional study. BMC Geriatrics, 23(1), Article 75. https://doi.org/10.1186/s12877-023-03768-7 PMid:36740694; PMCid:PMC9900971

Marcum, Z. A., Hanlon, J. T., & Murray, M. D. (2017). Improving medication adherence and health outcomes in older adults: An evidence-based review of randomized controlled trials. Drugs & Aging, 34(3), 191–201. https://doi.org/10.1007/s40266-016-0433-7 PMid:28074410; PMCid:PMC5325769

Marengoni, A., Angleman, S., Melis, R., Mangialasche, F., Karp, A., Garmen, A., Meinow, B., & Fratiglioni, L. (2011). Aging with multimorbidity: A systematic review of the literature. Ageing Research Reviews, 10(4), 430–439. https://doi.org/10.1016/j.arr.2011.03.003 PMid:21402176

Marengoni, A., Monaco, A., Costa, E., Cherubini, A., Prados-Torres, A., Muth, C., Melis, R. J. F., Pasina, L., van der Cammen, T. J. M., Palmer, K., Pecorelli, S., & Onder, G. (2016). Strategies to improve medication adherence in older persons: Consensus statement from the Senior Italia Federanziani Advisory Board. Drugs & Aging, 33(9), 629–637. https://doi.org/10.1007/s40266-016-0387-9 PMid:27444182

Maresova, P., Javanmardi, E., Barakovic, S., Barakovic Husic, J., Tomsone, S., Krejcar, O., & Kuca, K. (2019). Consequences of chronic diseases and other limitations associated with old age: A scoping review. BMC Public Health, 19(1), Article 1431. https://doi.org/10.1186/s12889-019-7762-5 PMid:31675997; PMCid:PMC6823935

Midao, L., Giardini, A., Menditto, E., Kardas, P., & Costa, E. (2017). Adherence to medication in older adults as a way to improve health outcomes and reduce healthcare system spending. In G. D'Onofrio, A. Greco, & D. Sancarlo (Eds.), Gerontology. IntechOpen. https://doi.org/10.5772/intechopen.72070 PMid:30015057

Minkin, A., Snider-Meyer, J., Olson, D., Gresser, S., Smith, H., & Kier, F. J. (2014). Effectiveness of a motivational interviewing intervention on medication compliance. Home Healthcare Nurse, 32(8), 490–496. https://doi.org/10.1097/NHH.0000000000000128 PMid:25171241

Ni, Z., Wu, B., Yang, Q., Yan, L. L., Liu, C., & Shaw, R. J. (2022). An mHealth intervention to improve medication adherence and health outcomes among patients with coronary heart disease: Randomized controlled trial. Journal of Medical Internet Research, 24(3), Article e27202. https://doi.org/10.2196/27202 PMid:35262490; PMCid:PMC8943565

Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., & Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, Article n71. https://doi.org/10.1136/bmj.n71 PMid:33782057; PMCid:PMC8005924

Park, E., & Kim, J. (2016). The impact of a nurse-led home visitation program on hypertension self-management among older community-dwelling Koreans. Public Health Nursing, 33(1), 42–52. https://doi.org/10.1111/phn.12220 PMid:26250719

Petrović, M., Osmančević, B., Ličen, S., Karnjuš, I., & Prosen, M. (2021). Oblikovanje modela medpoklicnega sodelovanja medicinskih sester na področju zagotavljanja farmacevtske skrbi: kvalitativna opisna raziskava. Obzornik zdravstvene nege, 55(2), 92–101. https://doi.org/10.14528/snr.2021.55.2.3034

Pherson, E., Roth, J., Nkimbeng, M., Boyd, C., & Szanton, S. L. (2018). Ensuring safe and optimal medication use in older community residents: Collaboration between a nurse and a pharmacist. Geriatric Nursing, 39(5), 554–559. https://doi.org/10.1016/j.gerinurse.2018.03.004 PMid:29653771

Polit, D. F., & Beck, C. T. (2018). Essentials of nursing research: Appraising evidence for nursing practice. Wolters Kluwer Health.

Previdoli, G., Cheong, V. L., Alldred, D., Tomlinson, J., Tyndale-Biscoe, S., Silcock, J., Fylan, F., Latif, A., Mangin, D., Benson, H., Davies, L., El-Farargy, N., Latif, Z., Okwen, P. M., Rutter, P., Subramanian, D., Tanna, S., Taylor, J., Thomas, S. K., & Fylan, B. (2023). A rapid review of interventions to improve medicine self-management for older people living at home. Health Expectation, 26(3), 945–988. https://doi.org/10.1111/hex.13729 PMid:36919190; PMCid:PMC10154809

Punnapurath, S., Vijayakumar, P., Platty, P. L., Krishna, S., & Thomas, T. (2021). A study of medication compliance in geriatric patients with chronic illness. Journal of Family Medicine and Primary Care, 10(4), 1644–1648. https://doi.org/10.4103/jfmpc.jfmpc_1302_20 PMid:34123906; PMCid:PMC8144798

Ravi, P., Pfaff, K., Ralph, J., Cruz, E., Bellaire, M., & Fontanin, G. (2022). Nurse-pharmacist collaborations for promoting medication safety among community-dwelling adults: A scoping review. International Journal of Nursing Studies Advances, 4, Article 100079. https://doi.org/10.1016/j.ijnsa.2022.100079 PMid:38745597; PMCid:PMC11080473

Reeder, B., Demiris, G., & Marek, K. D. (2013). Older adults' satisfaction with a medication dispensing device in home care. Informatics for Health and Social Care, 38(3), 211–222. https://doi.org/10.3109/17538157.2012.741084 PMid:23323721; PMCid:PMC4122419

Ruppar, T. M., Conn, V. S., & Russell, C. L. (2008). Medication adherence interventions for older adults: Literature review. Research and Theory for Nursing Practice, 22(2), 114–147. https://doi.org/10.1891/1541-6577.22.2.114 PMid:18578221

Ruppar, T. M., Dobbels, F., Lewek, P., Matyjaszczyk, M., Siebens, K., & De Geest, S. M. (2015). Systematic review of clinical practice guidelines for the improvement of medication adherence. International Journal of Behavioral Medicine, 22(6), 699–708. https://doi.org/10.1007/s12529-015-9479-x PMid:25805550

Sapkota, S., Brien, J. A., Greenfield, J., & Aslani, P. (2015). A systematic review of interventions addressing adherence to anti-diabetic medications in patients with type 2 diabetes impact on adherence. PLoS One, 10(2), Article e0118296. https://doi.org/10.1371/journal.pone.0118296 PMid:2571046;5 PMCid:PMC4339210

Sheehan, O. C., Kharrazi, H., Carl, K. J., Leff, B., Wolff, J. L., Roth, D. L., Gabbard, J., & Boyd, C. M. (2018). Helping older adults improve their medication experience (home) by addressing medication regimen complexity in home healthcare. Home Healthcare Now, 36(1), 10–19. https://doi.org/10.1097/nhh.0000000000000632 PMid:29298192; PMCid:PMC5761673

Statistični urad Republike Slovenije. (SURS). (2025). Število in sestava prebivalstva. https://www.stat.si/statweb/Field/Index/17/104

Tong, A., Sainsbury, P., & Craig, J. (2007). Consolidated criteria for reporting qualitative research (COREQ): A 32-item checklist for interviews and focus groups. International Journal for Quality in Health Care, 19(6), 349–357. https://doi.org/10.1093/intqhc/mzm042

Turjamaa, R., Kapanen, S., & Kangasniemi, M. (2020). How smart medication systems are used to support older people's drug regimens: A systematic literature review. Geriatric Nursing, 41(6), 677–684. https://doi.org/10.1016/j.gerinurse.2020.02.005 PMid:32192722

Turjamaa, R., Vaismoradi, M., & Kangasniemi, M. (2023). Older home care clients' experiences of digitalisation: A qualitative study of experiences of the use of robot for medicines management. Scandinavian Journal of Caring Sciences, 37(2), 561–570. https://doi.org/10.1111/scs.13141

Van Camp, Y. P., Van Rompaey, B., & Elseviers, M. M. (2013). Nurse-led interventions to enhance adherence to chronic medication: Systematic review and meta-analysis of randomised controlled trials. European Journal of Clinical Pharmacology, 69(4), 761–770. https://doi.org/10.1007/s00228-012-1419-y PMid:23052418

Verloo, H., Chiolero, A., Kiszio, B., Kampel, T., & Santschi, V. (2017). Nurse interventions to improve medication adherence among discharged older adults: A systematic review. Age and Ageing, 46(5), 747–754. https://doi.org/10.1093/ageing/afx076 PMid:28510645

World Health Organization (WHO). (2003). Adherence to long term therapies: Evidence for action. World Health Organization.

Wilhelmsen, N. C., & Eriksson, T. (2019). Medication adherence interventions and outcomes: An overview of systematic reviews. European Journal of Clinical Pharmacology, 26(4), 187–192. https://doi.org/10.1136/ejhpharm-2018-001725 PMid:31338165; PMCid:PMC6613929

Willig, C., & Stainton Rogers, S. (2017). The Sage Handbook of Qualitative Research in Psychology. Sage Publications. https://doi.org/10.4135/9781526405555

Winland-Brown, J. E., & Valiante, J. (2000). Effectiveness of different medication management approaches on elders' medication adherence. Outcomes Management of Nursing Practice, 4(4), 172–176.

Zeitouny, S., Cheng, L., Wong, S. T., Tadrous, M., McGrail, K., & Law, M. R. (2023). Prevalence and predictors of primary nonadherence to medications prescribed in primary care. Canadian Medical Association Journal, 195(30), Article E1000. https://doi.org/10.1503/cmaj.221018 PMid:37553145; PMCid:PMC10446155

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26.09.2025

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Peršolja, M., Skočir, H., & Benko, E. (2025). Intervencije medicinskih sester za izboljšanje adherence pri starejših odraslih v domačem okolju: integrativni pregled literature. Obzornik Zdravstvene Nege, 59(3), 187–198. https://doi.org/10.14528/snr.2025.59.3.3305

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