Technical factors of intramuscular injection application
A systematic literature review
DOI:
https://doi.org/10.14528/snr.2021.55.4.3098Keywords:
adults, intervention, parenteral application, vaccination, muscleAbstract
Introduction: Intramuscular injection is the most commonly used method of injection. The purpose of the study was to examine the latest findings in the field of site preparation and application of intramuscular injection.
Methods: A systematic review of the scientific and professional literature was performed in the international databases CINAHL, PubMed, Cochrane Library and ScienceDirect. The following keywords were used: intramuscular injection, intramuscular vaccination, injection site, skin disinfection, injection technique. Boolean operators AND and OR were used in the search. The literature search was conducted in March and April 2021.
Results: Of the 4208 search results, 13 articles were included in the final analysis. The findings were grouped into 4 categories: (1) puncture site selection, (2) intramuscular injection techniques, (3) disinfection of the puncture site and (4) aspiration.
Discussion and conclusion: There is no common agreement regarding a safe and professional application of intramuscular injection among the authors of the reviewed studies. Research shows that the most suitable site of application is the ventrogluteal area. Disinfection of the puncture site before application is not necessary out of hospital, while aspiration is recommended only at the dorsogluteal site. The optimal application technique is the skin traction – pressure – rapid muscle release technique with selecting an appropriate needle size taking into account the thickness of the subcutaneous fat, the site of application and the density of the drug. Additional research should be conducted to unify the recommendations for the optimal intramuscular injection technique.
Downloads
Metrics
References
Chadwick, A., & Withnell, N. (2015). How to administer intramuscular injections. Nursing Standard, 30(8), 36–39. https://doi.org/10.7748/ns.30.8.36.s45 PMid:26488992
Cook, I. F. (2016). Sepsis, parenteral vaccination and skin disinfection. Human Vaccines & Immunotherapeutics, 12(10), 2546–2559. https://doi.org/10.1080/21645515.2016.1190489 PMid:27295449; PMCid:PMC5084982
Critical Appraisal Skills Programme (2021). CASP (cohort study, randomised controlled trials, systematic review) Checklist. Retreived March 4, 2021 from https://casp-uk.net/casp-tools-checklists/
Crawford, C. L., & Johnson, J. A. (2012). To aspirate or not: An integrative review of the evidence. Nursing, 42(3), 20-25. https://doi.org/10.1097/01.NURSE.0000411417.91161.87 PMid:22343951
Dulong, C., Brett, K., & Argáez, C. (2020). Skin preparation for injections: A review of clinical effectiveness, cost-effectiveness and guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health. Retreived March 3, 2021 from https:// www.ncbi.nlm.nih.gov/books/NBK562932/
Fink, A., Kobilšek, P. V., & Mesarec, M. (2013). Diagnostičnoterapevtski pristopi in fizika v medicini. Ljubljana: Grafenauer.
Gantar, B., & Vogrinc, J. (2008). Kvalitativno raziskovanje na pedagoškem področju. Univerza v Ljubljani, Pedagoška fakulteta, Ljubljana.
Gomes, B., Oroski, G., & Traverso, F. (2019). (Re)discussing the drug administration technique by the intramuscular route: A systematic review. Revista de Pesquisa: Cuidado é Fundamental Online, 11, 228. https://doi.org/10.9789/2175-5361.2019.v11i1.268-276
Greenway, K. (2014). Rituals in nursing: Intramuscular injections. Journal of Clinical Nursing, 23(23/24), 3583–3588. https://doi:10.1111/jocn.12627 PMid:24814160
Gülnar, E., & Özveren, H. (2016). An evaluation of the effectiveness of a planned training program for nurses on administering intramuscular injections into the ventrogluteal site. Nurse Education Today, 36, 360–363. https://doi.org/10.1016/j.nedt.2015.09.001 PMid:26438073
Hdaib, M. T., Al-Momany, S. M., & Najjar, Y. W. (2015). Knowledge level assessment and change among nursing students regarding administering intra-muscular injection at Al-Balqa'a Applied University: An interventional study. Nurse Education Today, 35(7), e18–22. https://doi.org/10.1016/j.nedt.2015.02.012 PMid:25743095
Hensel, D., & Springmyer, J. (2011). Do perinatal nurses still check for blood return when administering the hepatitis B vaccine. Journal of Obstetric, Gynecologic & Neonatal Nursing, 40(5), 589–594. https://doi.org/10.1111/j.1552-6909.2011.01277.x PMid:22273415
Heshmatifar, N., Salari, M., Rad, M., Afshari Saleh, T., Borzoee, F., & Rastaghi, S. (2021). A new approach on the pain management of intramuscular injection: A triple-blind randomized clinical trial. Pain Management Nursing, in press. https://doi.org/10.1016/j.pmn.2021.01.010 PMid:33714700
Kara, D., & Güneş, Ü. Y. (2016). The effect on pain of three different methods of intramuscular injection: A randomized controlled trial. International Journal of Nursing Practice, 22(2), 152–159. https://doi.org/10.1111/ijn.12358 PMid:25039702
Kara, D., Uzelli, D., & Karaman, D. (2015). Using ventrogluteal site in intramuscular injections is a priority or an alternative. International Journal of Caring Sciences, 8(2), 507–513.
Kaya, N., Turan, N., & Aydin, G. O. (2016). Ventrogluteal site injection: a systematic review. International Journal of Caring Sciences, 9(3), 1168–1176.
Khawaja, R. A., Sikandar, R., Qureshi, R., & Jareno, R. J. M. (2013). Routine skin preparation with 70% isopropyl alcohol swab: Is it necessary before an injection: Quasi study. Journal of Liaquat University of Medical & Health Sciences, 12(2), 109–114.
Kodeks etike v zdravstveni negi in oskrbi Slovenije in Kodeks etike za babice Slovenije. (2014). Ljubljana: Zbornica zdravstvene in babiške nege Slovenije – Zveza strokovnih društev medicinskih sester, babic in zdravstvenih tehnikov Slovenije.
McDaniels, A., & Pittman, D. (2011). Is skin preparation necessary before needling. Medical Acupuncture, 23(1). https://doi.org/10.1089/acu.2010.0783
Mekkawy, M. M., Khalil, S. S., Diab, T. M., & Abdelaal, E. M. (2019). Nurses' practice for selection the site and painless intramuscular injections in Upper Egypt. International journal of Advance Research in Nursing, 2(1), 39–45.
Ogston-Tuck, S. (2014). Intramuscular injection technique: An evidence-based approach. Nursing Standard, 29(4), 52–59. https://doi.org/10.7748/ns.29.4.52.e9183 PMid:25249123
Öztürk, D., Baykara, Z. G., Karadag, A., & Eyikara, E. (2017). The effect of the application of manual pressure before the administration of intramuscular injections on students' perceptions of postinjection pain: A semi-experimental study. Journal of Clinical Nursing, 26(11–12), 1632–1638. https://doi.org/10.1111/jocn.13530 PMid:27535654
Perry, A. G., Potter, P. A., & Ostendorf, W. (2013). Clinical Nursing Skills and Techniques. Maryland Heights: Mosby.
Polishchuk, D., Gehrmann, R., & Tan, V. (2012). Skin sterility after application of ethyl chloride spray. The journal of Bone and Joint Surgery. American volume, 94(2), 118–120. https://doi.org/10.2106/JBJS.K.00229 PMid:22257997
Sari, D., Şahin, M., Yaşar, E., Taşkiran, N., & Telli, S. (2017). Investigation of Turkish nurses frequency and knowledge of administration of intramuscular injections to the ventrogluteal site: Results from questionnaires. Nurse Education Today, 56, 47–51. https://doi.org/10.1016/j.nedt.2017.06.005 PMid:28666144
Senekovič, A., Fekonja, Z., & Vrbnjak, D. (2020). Varnost pri aplikaciji intramuskularne injekcije. Obzornik zdravstvene nege, 54(2), 164–177. https://doi.org/10.14528/snr.2020.54.2.3017
Sepah, Y., Samad, L., Altaf, A., Halim, M. S., Rajagopalan, N., & Javed Khan, A. (2014). Aspiration in injections: Should we continue or abandon the practice. F1000Research, 3, Article 157. https://doi.org/10.12688/f1000research.1113.1 PMid:28344770; PMCid:PMC5333604
Sisson, H. (2015). Aspirating during the intramuscular injection procedure: A systematic literature review. Journal of Clinical Nursing, 24(17–18), 2368–2375. https://doi.org/10.1111/jocn.12824 PMid:25871949
Thomas, C. M., Mraz, M., & Rajcan, L. (2016). Blood Aspiration During IM Injection. Clinical Nursing Research, 25(5), 549–559. https://doi:10.1177/1054773815575074 PMid:25784149
Welch, V., Petticrew, M., Tugwell, P., Moher, D., O'Neill, J., Waters, E. … the PRISMA-Equity Bellagio group. (2012). PRISMA-Equity 2012 Extension: Reporting Guidelines for systematic reviews with a focus on health equity. Public Library of Science Medicine, 9(10), Article e1001333. https://doi.org/10.1371/journal.pmed.1001333 PMid:23222917; PMCid:PMC3484052
Wong, H., Moss, C., Moss, S. M., Shah, V., Halperin, S. A., Ito, S. … Taddio, A. (2019). Effect of alcohol skin cleansing on vaccination-associated infections and local skin reactions: A randomized controlled trial. Human Vaccines & Immunotherapeutics, 15(4), 995–1002. https://doi.org/10.1080/21645515.2018.1553474 PMid:30513266; PMCid:PMC6605859
World Medical Association. (2013). World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. Journal of the American Medical Association, 310(20), 2191–2194. https://doi.org/10.1001/jama.2013.281053 PMid:24141714
Yilmaz, D., Khorshid, L., & Dedeoglu, Y. (2016). The effect of the Z-track technique on pain and drug leakage in intramuscular injections. Clinical Nurse Specialist, 30(6), E7. https://doi.org/10.1097/NUR.0000000000000245 PMid:27753676
Yoshida, Y., Takashima, R., & Yano, R. (2021). Is skin disinfection before subcutaneous injection necessary: The reasoning of certified nurses in infection control in Japan. Plos One, 16(1). https://doi.org/10.1371/journal.pone.0245202 PMid:33418557; PMCid:PMC7794031
Železnik, D., & Ivanuša, A. (2008). Standardi aktivnosti zdravstvene nege, 2. izdaja. Maribor: Fakulteta za zdravstvene vede.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Slovenian Nursing Review
This work is licensed under a Creative Commons Attribution 4.0 International License.
As the author undersigned hereby, I transfer, assign, or otherwise convey the following authorship rights as comprised in the Copyright and Related Rights Act (CRRA) to the Slovenian Nursing Review, Ob železnici 30A, 1000 Ljubljana: the right of reproduction - the exclusive right to fix the work in a material medium or in another copy directly or indirectly, temporarily or permanently, by any means and in any digital form, in whole or in part (CRRA, Article 23); the right of distribution (CRRA, Article 24); the right of making a work available and accessible through the internet (CRRA, Article 32a); the right of transformation, especially the exclusive right to translate a pre-existing work (CRRA, Article 33). The transfer of author rights applies to the article in its entirety, including pictorial and/or graphic works and possible supplements. The transfer of rights is exclusive and unlimited in duration or territory.